Garcinia Cambogia Side Effects
The famous or infamous Dr. Oz of television news broadcast fame presented his special brand of garcinia cambogia with the claim that the product was all natural, produced substantial weight loss, and had no side effects. Independent studies have proven that all these claims except the natural part are false.
Some of the Dr. Oz garcinia cambogia products have been withdrawn from the market due to damaging side effects. In all fairness the product that Dr. Oz promoted had not been completely tested by independent labs that had no financial interest in the product before it was marketed by Dr. Oz.
The product does not produce weight loss
A 1998 study that was published in the Journal of the American Medical Association proves beyond any doubt that the chemically active ingredient in garcinia cambogia called hydroxycitric acid failed to produce any substantial weight loss in people that were overweight or obese. The average weight loss was around four pounds in 13 weeks.
It is noteworthy to state that the study was available 14 years before Dr. Oz began marketing his ‘special” brand of garcinia cambogia. Other studies have shown that any weight loss from the use of garcinia cambogia do not persist after 13 weeks of use.
A 2004 meta-study (an analysis of all published studies from across the globe) found that weight loss was marginal if not nonexistent in more than 6,000 people that had taken garcinia cambogia for between six months and five years. The compound does not produce the weight loss that it is claimed to produce and is not considered an obesity cure. A 2012 study published in the journal Food Science and Nutrition found similar results.
In 2013 just one year after Dr. Oz claimed that garcinia cambogia produced no side effects, researchers conducted a study of the active component in mice that was reported in the World Journal of Gastroenterology. The study was done in mice that were forced to eat a high fat diet along with garcinia cambogia that was adjusted to be equal to the daily amount recommended for people by weight. The mice in the study had no liver irregularities when the study began.
The study found that long-term use of garcinia cambogia produced cirrhosis of the liver, inflammation of the liver, and increased the level of oxidative stress on the liver. The changes in enzyme production in the liver and the loss of normal liver function seen in the test mice due to oxidative stress were equivalent to long-term alcohol abuse as seen in humans and the effects that hepatitis has on the liver. The drug did produce a modest weight loss in the test mice.
One might say that mice are not people. Research has proven that the metabolic functions of a mouse body are so similar to the human body that reasonable comparisons can be made between mouse reactions to a drug and potential human reactions to the same drug.
A 2009 study reported in the World Journal of Gastroenterology cited extreme cases of liver toxicity that promoted cirrhosis of the liver, inflammation of the liver, jaundice, and increased the level of oxidative stress on the liver in people that had used garcinia cambogia for five years.
The same study noted that fatigue, abdominal cramps, nausea without vomiting, anorexia, and fever had been seen in the majority of people that used garcinia cambogia. Other studies have indicated that dry mouth and dizziness are common side effects of the “medicine”.
One should note that anorexia can be a deadly disease and while the subjects that reported anorexia as a result of taking garcinia cambogia may have been prone to anorexia the fact that the medicine claims to have no side effects could make it potentially deadly for anorexic individuals.
A 2005 study published in the journal Food and Chemical Toxicology found substantial testicular atrophy in men that used garcinia cambogia for as little as two years. The amounts of garcinia cambogia consumed were equivalent to the recommended daily amounts found on the bottle of the over-the-counter weight loss drug. Testicular atrophy can reduce the capacity of a man to produce sufficient sperm to produce a child and can lead to cancer of the testicles.
Side effects should include drug interactions. Any over-the-counter medication that interferes with a prescription drug in any way should be noted on the information for the weight loss drug but no such warning is included in any version of garcinia cambogia.
Clinical studies have found that garcinia cambogia interferes with the function of insulin for treatment of diabetes, inhalants that treat asthma, iron taken for anemia, depression medications, anxiety medications, antipsychotics, cholesterol lowering drugs of the statin variety, some kidney medications, and warfarin taken for heart disease.
The fact that no indication of complications from taking garcinia cambogia has been shown for any of these drugs can produce severe and deadly effects on people that take garcinia cambogia not knowing that the active compound in garcinia cambogia interferes with drugs that keep them alive and healthy.
The claim that garcinia cambogia has no side effects is totally bogus. The evidence that the product caused liver function problems was available just after Dr. Oz began his marketing campaign on television. The evidence that the weight loss produced by garcinia cambogia was inconsequential at best was available before Dr. Oz promoted his miracle weight loss nostrum.
Garcinia cambogia still carries no formal warnings from the U. S. Food and Drug Administration and while Dr. Oz has ceased pushing the “medicine”, it can be readily obtained at most health food stores sand on the internet.